D97703
Diethyl maleate
97%
Synonym(s):
Maleic acid diethyl ester
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All Photos(3)
About This Item
Linear Formula:
C2H5OCOCH=CHCOOC2H5
CAS Number:
Molecular Weight:
172.18
Beilstein:
1100825
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
vapor density
5.93 (vs air)
vapor pressure
1 mmHg ( 14 °C)
Assay
97%
form
liquid
autoignition temp.
662 °F
refractive index
n20/D 1.441 (lit.)
bp
225 °C (lit.)
mp
−10 °C (lit.)
density
1.064 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)\C=C/C(=O)OCC
InChI
1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5-
InChI key
IEPRKVQEAMIZSS-WAYWQWQTSA-N
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General description
Diethyl maleate is an ester derived from maleic anhydride, used as a building block in the synthesis of pyromellitic acid.
Application
- Retrospective analysis of pesticide metabolites in urine using liquid chromatography coupled to high-resolution mass spectrometry.: This study highlights the use of diethyl maleate in the analysis of pesticide metabolites, demonstrating its application in high-resolution mass spectrometry for detecting urinary pesticide metabolites (Lapez et al., 2016).
- Diethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways.: Research on the inhibition of cancer cell growth by diethyl maleate, focusing on its effects on glutathione, MAPK pathways, and its potential therapeutic applications in cancer treatment (Priya et al., 2014).
- Hepatic transcriptome and proteome responses against diethyl maleate-induced glutathione depletion in the rat.: This study explores the effects of diethyl maleate on liver cells, emphasizing its role in depleting glutathione and its implications for oxidative stress and liver toxicity (Yamauchi et al., 2011).
- Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems.: This paper discusses the innovative application of diethyl maleate in NMR spectroscopy for accurate determination of coupling constants, enhancing the analysis of complex spin systems (Williamson et al., 2000).
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
200.1 °F - closed cup
Flash Point(C)
93.4 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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