Skip to Content
Merck
All Photos(1)

Documents

925462

Sigma-Aldrich

Maleimide poly(ethylene glycol)-block-poly(lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 15,000, lactide:glycolide 50:50

Synonym(s):

Maleimide-PEG-b-PLGA, Maleimide-PEG-PLGA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C13H19SN2O4(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]m
UNSPSC Code:
12352111
NACRES:
NA.23

feed ratio

50:50±5 (Lactide:Glycolide, by NMR)
lactide:glycolide 50:50

Quality Level

100

mol wt

PEG Mn 4000-6000 g/mol (by NMR)
PEG average Mn 5,000
PLGA Mn 12000-18000 g/mol
PLGA average Mn 15,000

suitability

conforms to structure for NMR

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Maleimide poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a maleimide-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the maleimide-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service