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914126

Sigma-Aldrich

Silica nanoparticles

pore size non-porous, 300 nm particle size, 5 % (w/w) in water, dispersion

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica

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About This Item

Empirical Formula (Hill Notation):
SiO2
CAS Number:
7631-86-9
Molecular Weight:
60.08
MDL number:
MFCD00011232
UNSPSC Code:
12352309
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

concentration

5 % (w/w) in water

particle size

300 nm

pore size

non-porous

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse nonporous silica in aqueous solution, with sizes varying from 150 nm to 900 nm. The high monodispersity of our particles makes them suitable for aforementioned applications.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H373

Precautionary Statements

P260 - P314 - P501

Hazard Classifications

STOT RE 2 Inhalation

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zhigang Xu et al.
Nanoscale, 7(13), 5859-5868 (2015-03-12)
A myriad of drug delivery systems such as liposomes, micelles, polymers and inorganic nanoparticles (NPs) have been developed for cancer therapy. Very few of them, however, have the ability to integrate multiple functionalities such as specific delivery, high circulation stability
Li Tang et al.
Nano today, 8(3), 290-312 (2013-09-03)
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in

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