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407038

Sigma-Aldrich

Poly(ethylene glycol) bis(carboxymethyl) ether

average MN 600, cross-linking reagent amine reactive, carboxylic acid

Synonym(s):

Polyethylene glycol, Polyethylene glycol 600 diacid, Polyglycol 600 diacid

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About This Item

Linear Formula:
HOOCCH2(OCH2CH2)nOCH2COOH
CAS Number:
39927-08-7
MDL number:
MFCD00132002
UNSPSC Code:
12162002
PubChem Substance ID:
24865420
NACRES:
NA.23

product name

Poly(ethylene glycol) bis(carboxymethyl) ether, average Mn 600

form

viscous liquid

mol wt

average Mn 600

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

density

1.191 g/mL at 25 °C

Ω-end

carboxylic acid

α-end

carboxylic acid

polymer architecture

shape: linear
functionality: homobifunctional

SMILES string

OCCO.OCC(O)=O

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

572.0 °F - closed cup

Flash Point(C)

300 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG6836
BCCG0907
BCCF3855
BCCF1931
BCCD7028

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Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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