122513

2-Amino-3-hydroxypyridine

98%

• Synonym(s): 2-Amino-3-pyridinol
• Empirical Formula (Hill Notation): C₅H₆N₂O
• CAS Number: 16867-03-1
• Molecular Weight: 110.11
• Beilstein: 109868
• EC Number: 240-886-8
• MDL number: MFCD00006317
• UNSPSC Code: 12352100
• eCl@ss: 39151903
• PubChem Substance ID: 24847493
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• mp: 168-172 °C (lit.)
• SMILES string: Nc1ncccc1O
• InChI: 1S/C5H6N2O/c6-5-4(8)2-1-3-7-5/h1-3,8H,(H2,6,7)
• InChI key: BMTSZVZQNMNPCT-UHFFFAOYSA-N

Description

General description

2-Amino-3-hydroxypyridine forms complexes with number of transition metals. It inhibits the corrosion of aluminium and copper in acidic solutions. It undergoes condensation with 2-hydroxy-1-naphthaldehyde and 2-hydroxybenzaldehyde to form Schiffs bases. It is useful in the preparation of clinical anti-inflammatory analgesics.

Application

2-Amino-3-hydroxypyridine was used as reagent in reaction of dimethyl acetylenedicarboxylate and triphenylphosphine to yield functionalized coumarins and 1,4-oxazines.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 - H315 - H319
• Precautionary Statements: P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves