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Key Documents

PLA0021

Sigma-Aldrich

Rabbit anti-CDC25a Antibody, Affinity Purified

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About This Item

UNSPSC Code:
12352203

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

concentration

1 mg/mL

technique(s)

immunoprecipitation (IP): 1- 4 μg/mg
western blot: 1:1,000- 1:10,000

accession no.

NP_001780.2

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... CDC25a(993)

Immunogen

The epitope recognized by PLA0021 maps to a region between residues 250 and 300 of human Cell Division Cycle 25A using the numbering given in entry NP_001780.2 (GeneID 993).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

CDC25a is a member of the CDC25 family of protein phosphatases. CDC25 is involved in promoting the G1 to S phase as well as the G2 to M phase transition of the cell cycle by removing inhibitory phosphates from tyrosine and threonine residues of cyclin-dependent kinases (CDKs). CDC25a is an oncogene and has been found to be overexpressed in a subset of human cancers.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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