H1009

Hydrogen peroxide solution

30 % (w/w) in H₂O, contains stabilizer

• Empirical Formula (Hill Notation): H₂O₂
• CAS Number: 7722-84-1
• Molecular Weight: 34.01
• Beilstein: 3587191
• MDL number: MFCD00011333
• UNSPSC Code: 12352304
• PubChem Substance ID: 57654227
• NACRES: NA.77

Properties

• vapor pressure: 23.3 mmHg ( 30 °C)
• Assay: 29.0-32.0% (titration)
• form: liquid
• shelf life: ~2 yr
• reaction suitability: reagent type: oxidant
• concentration: 30 % (w/w) in H₂O
• technique(s): cell based assay: suitable; immunohistochemistry: suitable
• density: 1.110 g/cm³
• suitability: suitable for DNA precipitation
• application(s): general analytical; pharmaceutical
• storage temp.: 2-8°C
• SMILES string: OO
• InChI: 1S/H2O2/c1-2/h1-2H
• InChI key: MHAJPDPJQMAIIY-UHFFFAOYSA-N

Description

General description

Hydrogen peroxide (H₂O₂), a topical antiseptic, is synthesized in aerobic cells as a byproduct of aerobic respiration. It might also be produced as an output of enzymatic reactions in peroxisomes, mitochondria, or other cell compartments.

Application

Hydrogen peroxide solution has been used:

• to treat nasal epithelial cells for H₂O₂ sensitivity assays
• to treat the human immortal keratinocyte cell line (HaCaT) and the human melanoma cell line (GLL19) to induce senescence
• to incubate brain sections for bromodeoxyuridine (BrdU)/NeuN staining
• in cell proliferation assay to incubate neural stem cells (NE-4C) for in vitro experiments

Biochem/physiol Actions

Hydrogen peroxide (H₂O₂) is mainly used in wound cleaning. It can kill the pathogens through oxidation burst and by producing local oxygen. H₂O₂ functions as a signaling molecule or second messenger. It plays a key role in gene expression in numerous ways. H₂O₂ participates in modulating inflammation.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

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Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318,H412
• Precautionary Statements: P273 - P280 - P305 + P351 + P338 - P501
• Hazard Classifications: Aquatic Chronic 3 - Eye Dam. 1
• Storage Class Code: 5.1B - Oxidizing hazardous materials
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves