75490
DL-Ornithine monohydrochloride
≥99.0% (AT)
Synonym(s):
(±)-2,5-Diaminopentanoic acid monohydrochloride
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About This Item
Linear Formula:
NH2(CH2)3CH(CO2H)(NH2) · HCl
CAS Number:
Molecular Weight:
168.62
Beilstein:
4153338
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
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Assay
≥99.0% (AT)
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
~233 °C (dec.)
application(s)
peptide synthesis
SMILES string
Cl.NCCCC(N)C(O)=O
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H
InChI key
GGTYBZJRPHEQDG-UHFFFAOYSA-N
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Application
DL-Ornithine monohydrochloride may be used as a starting material in the synthesis of (-)-(1-2H)putrescine dihydrochloride via enzymatic decarboxylation.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The Stereochemistry of the Enzymic Decarboxylation of l-Arginine and of l-Ornithine
Richards JC and Spenser ID
Canadian Journal of Chemistry, 60(22), 2810-2820 (1982)
Juan C Marini et al.
American journal of physiology. Endocrinology and metabolism, 303(11), E1348-E1353 (2012-10-18)
Citrulline is an amino acid synthesized in the gut and utilized for the synthesis of the conditionally essential amino acid arginine. Recently, the origin of the ornithine utilized for citrulline synthesis has become a matter of discussion. Multiple physiological factors
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
D Amelio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 164(2), 356-362 (2012-11-06)
The Frank-Starling law is a fundamental property of the vertebrate myocardium which allows, when the end-diastolic volume increases, that the consequent stretch of the myocardial fibers generates a more forceful contraction. It has been shown that in the eel (Anguilla
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