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MilliporeSigma

1366002

USP

Lidocaine

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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About This Item

Fórmula empírica (notación de Hill):
C14H22N2O
Número de CAS:
Peso molecular:
234.34
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lidocaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lidocaine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard and system suitability solution for assay, identification and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Lidocaine
  • Lidocaine Hydrochloride Topical Solution
  • Lidocaine Hydrochloride Oral Topical Solution
  • Lidocaine Hydrochloride Jelly

Biochem/physiol Actions

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Lidocaine Hydrochloride Oral Topical Solution
United States Pharmacopeia, 44(4), 2626-2626 (2020)
Lidocaine Hydrochloride Jelly
United States Pharmacopeia, 43(6), 2625-2625 (2020)
Daniela Casoni et al.
Veterinary anaesthesia and analgesia, 42(3), 250-259 (2014-07-22)
To determine the potency ratio between S-ketamine and racemic ketamine as inductive agents for achieving tracheal intubation in dogs. Prospective, randomized, 'blinded', clinical trial conducted in two consecutive phases. 112 client-owned dogs (ASA I or II). All animals were premedicated
Bartholomeus C M Benno Haarman et al.
Brain, behavior, and immunity, 40, 219-225 (2014-04-08)
The "monocyte-T-cell theory of mood disorders" regards neuroinflammation, i.e. marked activation of microglia, as a driving force in bipolar disorder. Microglia activation can be visualized in vivo using [(11)C]-(R)-PK11195 PET. Indirect evidence suggests the hippocampus as a potential focus of
Song-Young Park et al.
American journal of physiology. Heart and circulatory physiology, 307(3), H346-H352 (2014-06-08)
Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles.

Artículos

The benefit of HILIC over traditional reversed-phase chromatography is two-fold for both sample introduction and analyte detection. First, the high acetonitrile concentration of HILIC mobile phases allows for direct analysis of precipitated plasma samples without the need for additional sample solvent exchange. Second, the high acetonitrile content provides increased analyte response in positive ESI MS detection.

Contenido relacionado

HILIC mobile phases consist of a high composition of acetonitrile, which facilitates the direct analysis of precipitated plasma samples without the need for additional sample solvent exchange.

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