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MilliporeSigma

48670

Supelco

N-Nitrosodimethylamine solution

certified reference material, 200 μg/mL in methanol

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About This Item

Número de CAS:
MDL number:
UNSPSC Code:
12000000

grade

certified reference material
TraceCERT®

Quality Level

agency

EPA TO-7

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

200 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-30°C

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

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General description

N-Nitrosodimethylamine is a toxic type of N-nitrosamine, which can be commonly synthesized in vivo by intestinal microbiota type of microorganisms. It can undergo reduction to form dimethylamine using zero-valent metal ions like Fe and Zn in the presence of Cu(II) ions.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3


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Lactic acid bacteria directly degrade N-nitrosodimethylamine and increase the nitrite-scavenging ability in kimchi
Kim H-S, et al.
Food Control, 71, 101-109 (2017)
The role of Cu (II) in the reduction of N-nitrosodimethylamine with iron and zinc
Han Y, et al.
Chemosphere, 167, 171-177 (2017)
Maria José Farré et al.
Environmental science & technology, 46(23), 12904-12912 (2012-11-09)
UV-C radiation is the U.S. EPA recommended technology to remove N-nitrosodimethylamine (NDMA) during drinking and recycled water production. Frequently, H(2)O(2) is added to the treatment to remove other recalcitrant compounds and to prevent NDMA reformation. However, the transformation of NDMA
Xiaojie Gan et al.
Water research, 47(3), 1344-1352 (2013-01-05)
The objective of this study was to examine the potential of Magnetic Ion Exchange (MIEX(®)) technology for removing nitrogenous disinfection byproduct (N-DBP) precursors while minimizing carbonaceous DBP (C-DBP) precursors in (i) surface waters, and (ii) effluent impacted waters. Samples were
R Sferra et al.
European review for medical and pharmacological sciences, 16(11), 1484-1498 (2012-11-01)
Hepatic fibrosis is characterised by a progressive accumulation of fibrillar extracellular matrix (ECM) proteins, including collagen that occurs in chronic liver diseases. Transforming growth factor-beta1 (TGF-beta)/Smad3 signalling plays a major role in tissue fibrogenesis acting as a potent stimulus of

Artículos

Learn about LC-MS/MS method development to quantify NDMA impurity in valsartan drug substance using Titan™ C18 column based UHPLC separation

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