SRP0697

TAU-316 Protein

recombinant

• UNSPSC Code: 12352202
• NACRES: NA.77

Propiedades

• recombinant: expressed in E. coli
• assay: 70-95% (SDS-PAGE)
• form: frozen liquid
• mol wt: ~39 kDa
• concentration: 0.2 μg/μL
• accession no.: P10636-3
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... MAPT(4137)

Descripción

Application

Useful for kinase assay and Western blot.

Biochem/physiol Actions

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type ⁽¹⁾. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy ⁽²⁾.

Sequence

Full Length

Reconstitution

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Storage and Stability

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable