SML3325

Sob-AM2

≥98% (HPLC)

• Sinónimos: 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]-N-methylacetamide
• Fórmula empírica (notación de Hill): C₂₁H₂₇NO₃
• Número de CAS: 2128258-47-7
• Peso molecular: 341.44
• UNSPSC Code: 51111800
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC(C1=C(C=CC(CC2=C(C=C(C=C2C)OCC(NC)=O)C)=C1)O)C

Descripción

General description

Sob-AM2 is a methyl amide derivative and a central nervous system (CNS)- selective prodrug of Sobetirome. Even in the absence of monocarboxylate transporter 8 (Mct8), Sob-AM2 can penetrate the brain and exhibit thyromimetic effects. It can promote extensive myelin repair in the brain and spinal cord of mouse models with demyelination. Sob-AM2 and other thyromimetics may also stimulate triggering receptor expressed on myeloid cell-2 (TREM2) expression in macrophages and microglia.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable