SML3110

CRANAD-3

≥98% (HPLC)

• Sinónimos: (T-4)-[(1E,6E)-1,7-Bis[6-(diethylamino)-3-pyridinyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoroboron, CRANAD 3
• Fórmula empírica (notación de Hill): C₂₅H₃₁BF₂N₄O₂
• Número de CAS: 1561983-97-8
• Peso molecular: 468.35
• UNSPSC Code: 12352200

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: gray to black
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: FB(O1)(F)O=C(/C=C/C2=CN=C(N(CC)CC)C=C2)C=C1/C=C/C3=CC=C(N(CC)CC)N=C3

Descripción

Biochem/physiol Actions

CRANAD-3, a curcumin analog, is a brain barrier penetrant smart NIRF (near-infrared) probe for both soluble and insoluble Aβ (amyloid beta) species in vivo. CRANAD-3 could be used to monitor the decrease in Aβs after drug treatment in transgenic AD (APP/PS1) mice. CRANAD-3 is suitable for in vivo dually-amplify signal via chemiluminescence resonance energy transfer (DAS-CRET) with ADLumin-1 a brain blood barrier penetrant smart chemiluminescence probe for Aβs

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable