SML2906

ERGi-USU

≥98% (HPLC)

• Sinónimos: 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
• Fórmula empírica (notación de Hill): C₁₃H₉N₃OS
• Número de CAS: 1147-56-4
• Peso molecular: 255.30
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: faint brown to dark red
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• InChI: 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
• InChI key: IOMXCGDXEUDZAK-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3