SML2187

RL5a

≥98% (HPLC)

• Sinónimos: N2-[2-(2-Furanyl)-4-quinolinyl]-N1,N1-dimethyl-1,2-ethanediamine
• Fórmula empírica (notación de Hill): C₁₇H₁₉N₃O
• Número de CAS: 133671-66-6
• Peso molecular: 281.35
• MDL number: MFCD00929354
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to very dark brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N(CCNc1c2c(nc(c1)c3[o]ccc3)cccc2)(C)C
• InChI: 1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
• InChI key: CRGKLHXVNVZAPA-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

potent inhibitor of the replication licensing system.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3