SML1451

MI192 hydrochloride

≥98% (HPLC)

• Sinónimos: N-(2-Aminophenyl)-4-[(3,4-dihydro-4-methylene-1-oxo-2(1H)-isoquinolinyl)methyl]-benzamide hydrochloride, MI-192 hydrochloride
• Fórmula empírica (notación de Hill): C₂₄H₂₁N₃O₂ · xHCl
• Número de CAS: 1415340-63-4
• Peso molecular: 383.44 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825890
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to light brown
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: C=C(CN1CC2=CC=C(C(NC3=CC=CC=C3N)=O)C=C2)C4=CC=CC=C4C1=O
• InChI: 1S/C24H21N3O2/c1-16-14-27(24(29)20-7-3-2-6-19(16)20)15-17-10-12-18(13-11-17)23(28)26-22-9-5-4-8-21(22)25/h2-13H,1,14-15,25H2,(H,26,28)
• InChI key: GTLTXEIKQVWSRF-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

MI192 is a potent and selective histone deacetylase 3 (HDAc 3) inhibitor that inhibits IL-6 production in peripheral blood mononuclear cells (PBMCs) from rheumatoid arthritis (RA) but not healthy PBMCs.

MI192 is a potent and selective histone deacetylase 3 (HDAc 3) inhibitor.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable