SML0944

NK-252

≥98% (HPLC)

• Sinónimos: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N′-(2-pyridinylmethyl)-urea
• Fórmula empírica (notación de Hill): C₁₃H₁₁N₅O₃
• Número de CAS: 1414963-82-8
• Peso molecular: 285.26
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N(Cc3ncccc3)C(=O)Nc1nnc([o]1)c2[o]ccc2
• InChI: 1S/C13H11N5O3/c19-12(15-8-9-4-1-2-6-14-9)16-13-18-17-11(21-13)10-5-3-7-20-10/h1-7H,8H2,(H2,15,16,18,19)
• InChI key: FNSCFQXZZNCDAI-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

NK-252 is a very potent, specific activator of the transcription factor Nrf2, which activates antioxidant-associated genes. NK-252 induces expression of an antioxidant response element promoter driven reporter gene, and protects Huh-7 liver cells against H202 induced cytotoxicity.

NK-252 is a very potent, specific activator of the transcription factor Nrf2.

Features and Benefits

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Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable