SML0367

VK3-OCH3

≥98% (HPLC)

• Sinónimos: 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-naphthoquinone
• Fórmula empírica (notación de Hill): C₁₄H₁₄O₃S
• Número de CAS: 255906-59-3
• Peso molecular: 262.32
• MDL number: MFCD22575003
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825368
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: light orange to dark orange
• solubility: DMSO: 10 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: COCCSC1=C(C)C(=O)c2ccccc2C1=O
• InChI: 1S/C14H14O3S/c1-9-12(15)10-5-3-4-6-11(10)13(16)14(9)18-8-7-17-2/h3-6H,7-8H2,1-2H3
• InChI key: JTCRCMIBIBLUOK-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

VK3-OCH3 is an analog of Vitamin K3 (Menadione) with potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.

Información de seguridad

• pictograms: GHS09
• signalword: Warning
• hcodes: H400
• pcodes: P273 - P391 - P501
• Hazard Classifications: Aquatic Acute 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable