SML0234

Mitiglinide calcium

≥98% (HPLC)

• Sinónimos: (aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt, KAD 1229, Mitiglinide hemicalcium salt, S 21403, [2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt
• Fórmula empírica (notación de Hill): C₁₉H₂₄NO₃·0.5Ca
• Número de CAS: 145525-41-3
• Peso molecular: 334.44
• MDL number: MFCD09955408
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825247
• NACRES: NA.77

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +5 to +9° (c=1, MeOH)
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥10 mg/mL at warmed to 60 °C
• storage temp.: room temp
• SMILES string: O=C(C[C@H](Cc1ccccc1)C(=O)O[Ca]OC(=O)[C@H](CC(=O)N2C[C@H]3CCCC[C@H]3C2)Cc4ccccc4)N5C[C@H]6CCCC[C@H]6C5
• InChI: 1S/2C19H25NO3.Ca/c2*21-18(20-12-15-8-4-5-9-16(15)13-20)11-17(19(22)23)10-14-6-2-1-3-7-14;/h2*1-3,6-7,15-17H,4-5,8-13H2,(H,22,23);/q;;+2/p-2/t2*15-,16+,17-;/m00./s1
• InChI key: PMRVFZXOCRHXFE-FMEJWYFOSA-L

Descripción

Biochem/physiol Actions

Mitiglinide is a drug for the treatment of type 2 diabetes. It is a highly selective KATP channel antagonist Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)–sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable