SAB5702754

Anti-AGL Antibody, clone 8V9K5, Rabbit Monoclonal

• Sinónimos: AGL, GDE, glycogen debranching enzyme
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 8V9K5, monoclonal
• form: liquid
• mol wt: 175 kDa
• species reactivity: rat, rat, human
• concentration: 1.20 mg/mL
• technique(s): immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAVTVYTNYPFPGETFNREKFRSLDWENPTEREDDSDKYCKLNLQQSGSFQYYFLQGNE
• UniProt accession no.: P35573
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... AGL(178)

Descripción

General description

This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human AGL (P35573).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1