SAB5702242

Anti-CD70 Antibody, clone 7F4S5, Rabbit Monoclonal

• Sinónimos: CD27L, CD27LG, TNFSF7
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 7F4S5, monoclonal
• form: liquid
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): flow cytometry: 1:100 - 1:800; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• UniProt accession no.: P32970
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CD70(970)

Descripción

General description

CD70 is a member of the TNF family whose expression is upregulated on DCs upon maturation. Its only receptor, CD27, is expressed on T cells and NK cells. The CD70/CD27 pathway promotes effector CD8+ T cells responses (by sustaining survival of CTLs) and influences polarization of CD4+ T cells, as it represents an alternative IL-12-independent pathway of Th1 priming and suppresses effector Th17 function.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant protein of human CD70.

Application

WB, FC

Información de seguridad

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H317,H411
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 2 - Skin Sens. 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3