SAB5702076

Anti-TLR7 Antibody, clone 3G6S4, Rabbit Monoclonal

• Sinónimos: TLR7,TLR7-like
• UNSPSC Code: 12352203
• NACRES: NA.46
• clone: 3G6S4, monoclonal
• application: WB
• species reactivity: human
• technique(s): western blot: 1:500 - 1:2000

Propiedades

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 3G6S4, monoclonal
• form: liquid
• mol wt: 140 kDa
• species reactivity: human
• concentration: 0.85 mg/mL
• technique(s): western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: SKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV
• UniProt accession no.: Q9NYK1
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TLR7(51284)

Descripción

General description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 950-1049 of human TLR7 (Q9NYK1).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1