SAB5500044

Anti-CD169 antibody, Rabbit monoclonal

clone SP216, recombinant, expressed in proprietary host, affinity isolated antibody

• Sinónimos: Anti-CD169, Anti-SIGLEC-1, Anti-SN
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• recombinant: expressed in proprietary host
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: SP216, monoclonal
• species reactivity: human (tested)
• technique(s): immunohistochemistry: 1:100
• isotype: IgG
• UniProt accession no.: Q9BZZ2
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... SIGLEC1(6614)

Descripción

General description

CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.

Immunogen

Synthetic peptide derived from the internal region of human CD169 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable