SAB4504276

Anti-phospho-CDK5 (pTyr¹⁵) antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 33 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; western blot: 1:500-1:1000
• NCBI accession no.: Q00535
• UniProt accession no.: Q00535
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr15)
• Gene Information: human ... CDK5(1020)

Descripción

General description

Cyclin-dependent kinase 5 (CDK5) belongs to the CDKs family. Active CDK5 is present in pancreatic β cells, corneal epithelial cells and monocytes. This gene is mapped to human chromosome 7q36.

Immunogen

The antiserum was produced against synthesized peptide derived from human CDK5 around the phosphorylation site of Tyr15.

Immunogen Range: 1-50

Biochem/physiol Actions

Cyclin-dependent kinase 5 (CDK5) controls migration and neuronal plasticity. This protein participates in neuron migration, neurite outgrowth and support and synaptogenesis. It also helps in the development of lymphatic vessels. Suppressing Cdk5 promotes cell death of tumor-initiating cells.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable