SAB4301725

Anti-PKD2L1

affinity isolated antibody

• Sinónimos: PCL, PKD2L, PKDL, TRPP3
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous glycerol solution
• species reactivity: human
• technique(s): immunohistochemistry: 1:20-1:100
• accession no.: NP_057196
• UniProt accession no.: Q9P0L9
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PKD2L1(9033)

Descripción

General description

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) is also known as polycystin-L/ transient receptor potential polycystin-3 (TRPP3). It is expressed in brain, kidney, heart, skeletal muscle, spleen, testis, retina and in the bipolar neurons in the tongue taste buds. TRPP3 is present on the surface membrane and/or endoplasmic reticulum membrane of cells. It belongs to the PKD2 gene family. PKD2L1 is mapped to human chromosome 10q25.

Immunogen

Synthetic peptide of human PKD2L1

Biochem/physiol Actions

PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel) participates in hedgehog signaling, intestinal development and sour tasting. It controls ciliary Ca2⁺ concentration. Mutations in PKD2 results in autosomal dominant kidney disease (ADPKD).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable