SAB4200722

Anti-Band 3 antibody, Mouse monoclonal

clone BIII-136, purified from hybridoma cell culture

• Sinónimos: AE 1, Anion exchange protein 1, Anion exchanger 1, Band 3 anion transport protein, Solute carrier family 4 member 1
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• biological source: mouse
• Quality Level: 200
• antibody form: purified from hybridoma cell culture
• antibody product type: primary antibodies
• clone: BIII-136, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): immunoblotting: 2-4 μg/mL (human erythrocytes ghosts extract); immunoprecipitation (IP): suitable
• isotype: IgG2a
• UniProt accession no.: P02730
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SLC4A1(6521)

Descripción

General description

Anti-Band 3 antibody, Mouse monoclonal (mouse IgG2a isotype) is derived from the BIII-136 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with glycophorin B purified from human erythrocytes.

Application

Anti-Band 3 antibody, Mouse monoclonal may be used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

As a response to an oxidative stress, Band 3 protein forms clusters and clear damaged and aged RBCs from circulation. Enhanced band 3 protein clustering is implicated in RBC disorders such as hemolytic anemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, malaria and sickle-cell disease.

Physical form

Glycophorin B purified from human erythrocytes

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable