SAB2900334
Anti-HSP90AA1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Sinónimos:
heat shock protein hsp 90-alpha, hsp 86, hsp90a, hspc1, hspca
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Productos recomendados
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse, chicken, monkey, Drosophila
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HSP90AA1(3320)
General description
Heat shock protein 90 (Hsp90α) gene is mapped to human chromosome 14q32.31. Hsp90α is an isoform of Hsp90 and is a cytoplasmic protein that comprises three domains, namely C-terminal, middle domain, and N-terminal nucleotide-binding domain. This protein is associated with membrane microdomains and lipid rafts.
Immunogen
Synthetic peptide from human HSP90AA1 / Hsp90.
Application
Anti-HSP90AA1 antibody produced in rabbit has been used in immunohistochemistry at a dilution of 1:400.
Biochem/physiol Actions
Heat shock protein 90 alpha family class A member 1 (HSP90AA1 or Hsp90α) is upregulated during stress and helps in survival from membrane stress, especially during drug targeting. It elicits cytoprotective function and mediates protein homeostasis in the cytoplasm. An elevated level of Hsp90α is observed during chronic obstructive pulmonary disease (COPD). Hsp90α also favors spermatocyte maturation and human ether-a-go-go-related gene (hERG) ion channel maturation.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Referencia del producto
Descripción
Precios
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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