SAB2501441

Anti-MYO5A antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-GS1, Anti-MYH12, Anti-MYO5, Anti-MYR12, Myosin VA (heavy chain 12, myoxin)
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, pig, bovine, mouse, rat
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: Q9Y4I1
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MYO5A(4644)

Descripción

General description

Myosin VA gene is mapped to human chromosome 15q21.2. It is a two-headed actin-based processive motor protein. Myosin VA comprises two heavy chains. Each chain has N-terminal motor domain, a neck region with six light chains and a coiled-coil and globular domain comprising tail region.

Immunogen

Peptide with sequence ETKQLELDLN, from the internal region of the protein sequence according to NP_000250.3; NP_001135967.1

Biochem/physiol Actions

Myosin VA associates with the microtubule-based motors and mediates organelle transport. It associates with Ras-related protein Rab-10 and mediates the glucose transporter type 4 translocation to plasma membrane. Mutations in the myosin VA is implicated in hypopigmentation disorder, Griscelli syndrome (GS1) and Elejalde syndrome.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable