SAB2500302

Anti-DDAH2 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Sinónimos: Anti-DDAHII, Anti-Dimethylarginine dimethylaminohydrolase 2, Anti-G6a, Anti-NG30
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, human, rat
• technique(s): indirect ELISA: suitable; western blot: suitable
• UniProt accession no.: O95865
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... DDAH2(23564)

Descripción

General description

DDAH (Dimethylarginine dimethylaminohydrolase) exists as two isoforms; DDAH1, and DDAH2. Tissues expressing endothelial nitric oxide synthases is predominated by DDAH2.

Immunogen

Peptide with sequence SSLCLVLSTRPHS from the C Terminus of the protein sequence according to NP_039268.1.

Application

Anti-DDAH2 antibody produced in goat is suitable for indirect ELISA and western blot applications.

Biochem/physiol Actions

DDAH2 (Dimethylarginine dimethylaminohydrolase 2) Activity partly determines the cellular concentration of methylarginine. Concentration of ADMA (asymmetrical dimethylarginine) in endothelial cells is increased on the advent of pharmacological inhibition of DDAH, which also leads to the inhibition of NO-mediated endothelium dependent relaxation of blood vessels.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable