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RAB0734

Sigma-Aldrich

Human SHBG / Sex Hormone-binding Globulin ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.2 pmol/L
standard curve range: 1.229-300 pmol/L

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SHBG(6462)

Categorías relacionadas

General description

Serum sex hormone-binding globulin (SHBG) protein is a homodimer with a signal peptide and two laminin G-like domains. SHBG is produced by testis germ cells and released into the bloodstream by the liver. SHBG gene is located on human chromosome 17p13.1.

Application

Human SHBG/Sex Hormone-binding Globulin ELISA Kit has been used to measure serum sex hormone-binding globulin (SHBG) in whole blood samples. It has also been used to quantify SHBG in maternal peripheral and umbilical cord blood.

Biochem/physiol Actions

Serum sex hormone-binding globulin (SHBG) can bind and transport sex steroids and aid in modulating their biological active fraction. Direct action of SHBG modulates sex steroid actions in target cells. A low level of SHBG is detected in women with polycystic ovary syndrome (PCOS). The SHBG ELISA kit can be used for the quantitative measurement of sex hormone-binding globulin in cell culture supernatants, plasma and serum.

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

pictograms

Corrosion
GHS05

signalword

Warning

hcodes

H290

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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1453723
Fortunati N and Catalano MG
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2010)
Tracy Y Zhu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29(9), 2118-2129 (2014-03-20)
In this cross-sectional study, we investigated volumetric bone mineral density (vBMD), bone microstructure, and biomechanical competence of the distal radius in male patients with rheumatoid arthritis (RA). The study cohort comprised 50 male RA patients of average age of 61.1
Fangfang Wang et al.
EBioMedicine, 60, 102993-102993 (2020-09-20)
This study explored the mechanisms underlying altered neurobehavioural development of female offspring born to mothers with polycystic ovary syndrome (PCOS). In total, 20 women with PCOS and 32 healthy women who underwent caesarean deliveries with a single female foetus were

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