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R3631

Sigma-Aldrich

Anti-Rabbit IgG (whole molecule) antibody produced in sheep

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD00162781
UNSPSC Code:
12352203
NACRES:
NA.46

biological source

sheep

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

indirect ELISA: 1:10,000

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

IgG antibody subtype is the major serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.

Application

Anti-Rabbit IgG (whole molecule) antibody produced in sheep has been used in competitive enzyme linked immunosorbent assay (ELISA).

Biochem/physiol Actions

IgG antibody defends bacterial, fungal and viral infections. Maternal IgG can cross placenta and offers immune defense for the neonate against infections.

Other Notes

Antibody adsorbed with human IgG.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Development and validation of a highly sensitive RIA for zoledronic acid, a new potent heterocyclic bisphosphonate, in human serum, plasma and urine
Legay F, et al.
Journal of Pharmaceutical and Biomedical Analysis, 30(4), 897-911 (2002)
Francois Legay et al.
Journal of pharmaceutical and biomedical analysis, 30(4), 897-911 (2002-11-01)
Zoledronic acid is a new, highly potent bisphosphonate drug under clinical evaluation. A radioimmunoassay has been developed to determine zoledronic acid concentration in human serum, plasma, and urine. The assay utilizes rabbit polyclonal antisera against a zoledronic acid-BSA conjugate and
IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
Avery DT, et al.
Journal of Immunology, 181(3), 1767-1779 (2008)
Placental transfer of IgG subclasses in a Japanese population.
Hashira S, et al.
Pediatrics International, 42(4) (2000)
Gestur Vidarsson et al.
Frontiers in immunology, 5, 520-520 (2014-11-05)
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These
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