P0424

Prostaglandin F_2α tris salt

≥99%, synthetic, powder

• Sinónimos: (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF_2α−Tris
• Fórmula empírica (notación de Hill): C₂₀H₃₄O₅ · C₄H₁₁NO₃
• Número de CAS: 38562-01-5
• Peso molecular: 475.62
• Beilstein/REAXYS Number: 4087514
• EC Number: 254-002-3
• MDL number: MFCD00077863
• UNSPSC Code: 12352401
• eCl@ss: 42020658
• PubChem Substance ID: 24898103
• NACRES: NA.77

Propiedades

• biological source: synthetic
• assay: ≥99%
• form: powder
• color: white
• solubility: H₂O: 1 mg/mL; ethanol: 50 mg/mL
• functional group: carboxylic acid; hydroxyl
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1
• InChI key: IYGXEHDCSOYNKY-RZHHZEQLSA-N
• Gene Information: human ... PTGFR(5737)

Descripción

General description

Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.

Biochem/physiol Actions

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F_2α and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360FD
• pcodes: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges