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N8513

Sigma-Aldrich

L-Norleucine

suitable for amino acid analysis, BioReagent

Sinónimos:

(S)-(+)-2-Aminohexanoic acid, (S)-2-Aminocaproic acid

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About This Item

Fórmula lineal:
CH3(CH2)3CH(NH2)CO2H
Número de CAS:
327-57-1
Peso molecular:
131.17
Beilstein/REAXYS Number:
1721750
EC Number:
206-321-4
MDL number:
MFCD00064423
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24897682
NACRES:
NA.26

Nombre del producto

L-Norleucine, suitable for amino acid analysis, BioReagent

product line

BioReagent

Quality Level

200

form

powder or crystals

color

white

mp

>300 °C (lit.)

suitability

suitable for amino acid analysis

application(s)

detection

SMILES string

CCCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

InChI key

LRQKBLKVPFOOQJ-YFKPBYRVSA-N

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Application

Highly purified internal standard for all amino acid analysis methods.

Other Notes

Non-essential amino acid.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCF1095
BCBW9585
BCBR7862V
BCBP0837V
BCBJ7197V

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Jan Pícha et al.
Journal of enzyme inhibition and medicinal chemistry, 26(2), 155-161 (2010-06-29)
Ligands containing bulky aliphatic P1 residues exhibit a high affinity towards cytosolic leucine aminopeptidase, a bizinc protease of biomedical significance. According to this specificity, a series of phosphonic and phosphinic compounds have been put forward as novel putative inhibitors of
Haiyan Wei et al.
The journal of physical chemistry. B, 114(36), 11820-11826 (2010-08-24)
Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
L M FitzGerald et al.
Australian veterinary journal, 89(3), 95-100 (2011-02-18)
Four dogs presented with clinical signs of severe hepatic disease after consuming a commercial camel meat diet. Laboratory investigation revealed evidence of severe liver disease, including markedly increased serum alanine aminotransferase (ALT) activity and total bilirubin concentration, and prolonged clotting
Yu-Ying Yang et al.
Chemistry & biology, 17(11), 1212-1222 (2010-11-26)
The advances in bioorthogonal ligation methods have provided new opportunities for proteomic analysis of newly synthesized proteins, posttranslational modifications, and specific enzyme families using azide/alkyne-functionalized chemical reporters and activity-based probes. Efficient enrichment and elution of azide/alkyne-labeled proteins with selectively cleavable
Troy Cellmer et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(15), 6103-6108 (2011-03-29)
Determining the rate of forming the truly folded conformation of ultrafast folding proteins is an important issue for both experiments and simulations. The double-norleucine mutant of the 35-residue villin subdomain is the focus of recent computer simulations with atomistic molecular
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