MAK553

Fluorimetric cADP-Ribose Assay Kit

sufficient for 100 fluorometric tests

• UNSPSC Code: 41116104
• NACRES: NA.84

Propiedades

• detection method: fluorometric
• relevant disease(s): genitourinary disorders; neurological disorders; cardiovascular diseases; cancer
• shipped in: dry ice
• storage temp.: −20°C

Descripción

General description

cADP-ribose (cADPR) is a novel Ca2+ messenger derived from NAD+. ADP-riboxyl cyclase (ADPRC) catalyzes the synthesis of cADPR from NAD+, but the reaction can be reversed in the presence of high concentration of nicotinamide, producing NAD+ from cADPR stoichiometrically. The resultant NAD+ can be detected by the NAD probe. This makes monitoring cADPR in tissues and cell cultures possible in the low nM range. The NAD+ detection using NAD probe is specific to NAD+ and has no reaction to NADH. This assay can be performed in a convenient 96-well or 384-well microplate.

Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H315,H319,H334,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3