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M9375

Sigma-Aldrich

D-Methionine

≥98% (HPLC)

Sinónimos:

(R)-2-Amino-4-(methylmercapto)butyric acid, D-2-Amino-4-(methylthio)butanoic acid

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About This Item

Fórmula empírica (notación de Hill):
C5H11NO2S
Número de CAS:
348-67-4
Peso molecular:
149.21
Beilstein/REAXYS Number:
1722293
EC Number:
206-483-6
MDL number:
MFCD00002622
UNSPSC Code:
12352209
PubChem Substance ID:
24897327
NACRES:
NA.26

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white

mp

273 °C

application(s)

cell analysis
peptide synthesis

SMILES string

CSCC[C@@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

InChI key

FFEARJCKVFRZRR-SCSAIBSYSA-N

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Biochem/physiol Actions

D-methionine has been shown to rescue noise-induced hearing loss.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
SLCJ5245
SLCD7755
SLBW7174
SLBT8189
SLBR8286V

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Millipore

1.05707

L-Methionine

Kathleen Campbell et al.
Hearing research, 282(1-2), 138-144 (2011-09-20)
We have previously reported rescue from noise-induced auditory brainstem response (ABR) threshold shifts with d-methionine (d-met) administration 1 h after noise exposure. The present study investigated further d-met rescue intervals at 3, 5 and 7 h post-noise exposure. Chinchillas laniger were exposed
Audrey S Vanhove et al.
Applied and environmental microbiology, 86(11) (2020-03-30)
While only a subset of Vibrio cholerae strains are human diarrheal pathogens, all are aquatic organisms. In this environment, they often persist in close association with arthropods. In the intestinal lumen of the model arthropod Drosophila melanogaster, methionine and methionine
Calvin Wu et al.
Journal of neural transmission (Vienna, Austria : 1996), 121(7), 683-693 (2014-02-18)
Antioxidants are well known for their neuroprotective properties against reactive oxygen species in cortical neurons and auditory cells. We recently identified L-carnitine and D-methionine to be among agents that provide such protection. Here, we investigated their neuronal modulatory actions. We
Tobias Dörr et al.
PLoS genetics, 10(6), e1004433-e1004433 (2014-06-20)
The bacterial cell wall, which is comprised of a mesh of polysaccharide strands crosslinked via peptide bridges (peptidoglycan, PG), is critical for maintenance of cell shape and survival. PG assembly is mediated by a variety of Penicillin Binding Proteins (PBP)
Guo-Lin Chen et al.
Gene, 435(1-2), 53-62 (2009-04-07)
Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5'-UTR in gene expression regulation. This study aimed
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