Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Key Documents

View All Documentation

I9659

Sigma-Aldrich

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75014, purified immunoglobulin, lyophilized powder

Sinónimos:

Anti-IGF2, Anti-INSIGF

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

MDL number:
MFCD00162567
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

75014, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

western blot: 1-2 μg/mL

isotype

IgG2a

UniProt accession no.

P01344

storage temp.

−20°C

Gene Information

human ... IGF2(3481)

¿Está buscando productos similares? Visita Guía de comparación de productos

Immunogen

purified, E. coli-derived recombinant human insulin-like growth factor-II.

Biochem/physiol Actions

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Related product

Referencia del producto
Descripción
Precios

I2526

Insulin-like Growth Factor-II human, IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

I7276

Anti-Insulin-Like Growth Factor-II antibody produced in goat, affinity isolated antibody, lyophilized powder

I8904

Insulin-like Growth Factor-II from mouse, IGF-II, recombinant, expressed in E. coli, lyophilized powder

I2282

Anti-Insulin-Like Growth Factor-II antibody produced in goat, affinity isolated antibody, lyophilized powder

I9534

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in rat, clone 122404, purified immunoglobulin, lyophilized powder

I9784

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse, clone 75015, purified immunoglobulin, lyophilized powder

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Robert G Maki
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(33), 4985-4995 (2010-10-27)
Insulin-like growth factors were discovered more than 50 years ago as mediators of growth hormone that effect growth and differentiation of bone and skeletal muscle. Interest of the role of insulin-like growth factors in cancer reached a peak in the
Wendy Chao et al.
Cytokine & growth factor reviews, 19(2), 111-120 (2008-03-01)
Insulin-like growth factor II (IGF2) is perhaps the most intricately regulated of all growth factors characterized to date. Its gene is imprinted--only one allele is active, depending on parental origin--and this pattern of expression is maintained epigenetically in almost all
C J Rosen
Clinical chemistry, 45(8 Pt 2), 1384-1390 (1999-08-03)
The last decade has been characterized by a major investigative thrust into the physiology of two unique but ubiquitous peptides, insulin-like growth factor (IGF)-I and IGF-II. The regulatory systems that control the tissue bioactivity of the IGFs have been delineated
Ettore Capoluongo
The American journal of pathology, 178(1), 26-31 (2011-01-13)
Insulin and insulin-like growth factors (IGFs) are important regulators of energy metabolism and growth. Several findings have outlined an important role played by this family of molecules in both tumor maintenance and development. Despite the established contribution of the IGF

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico