I8398

Anti-Interleukin-2 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• Sinónimos: Anti-IL-2
• MDL number: MFCD00675261
• UNSPSC Code: 12352203
• NACRES: NA.46

Propiedades

• biological source: goat
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): neutralization: suitable; western blot: suitable
• UniProt accession no.: P04351
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Il2(16183)

Descripción

General description

The antibody neutralizes the biological activity of recombinant mouse interleukin-2, but not human interleukin-2.

Immunogen

recombinant mouse interleukin-2 expressed in Escherichia coli.

Biochem/physiol Actions

Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.