Saltar al contenido
MilliporeSigma
Todas las fotos(1)

Key Documents

View All Documentation

GW20079F

Sigma-Aldrich

Anti-Vitamin D-Binding Protein antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Sinónimos:

Anti-VDBP

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: suitable

NCBI accession no.

NP_000574.2

UniProt accession no.

P02774

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GC(2638)

Immunogen

Immunogen Sequence: GI # 32483410, sequence 1-474
Vitamin D-binding protein (native protein).

Application

Anti-Vitamin D-Binding Protein antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Vitamin D-binding protein (also known as gc-globulin) is a protein encoded by the GC gene in humans. It transports vitamin D metabolites in the circulation. Both vitamin D metabolites and vitamin D binding proteins (VDBP) are associated with asthma (regulation in the lung during acute allergen-induced airway inflammation). Vitamin D-binding protein (VDBP) haplotypes also influence free vitamin D levels.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

¿No encuentra el producto adecuado?  

Pruebe nuestro Herramienta de selección de productos.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Aledie Navas-Nazario et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(6), 519-524 (2014-04-22)
Potential vitamin D-related influences on inflammatory diseases such as asthma are controversial, including the suggestion that vitamin D insufficiency is associated with increased asthma morbidity. Vitamin D-binding protein transports vitamin D metabolites in the circulation. Single nucleotide polymorphisms in the
A G Randolph et al.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44(2), 231-237 (2014-01-23)
Between 75 000 and 125 000 U.S. infants are hospitalized for respiratory syncytial virus (RSV) bronchiolitis every year. Up to half will be diagnosed with asthma in later childhood. Vitamin D deficiency has been associated with susceptibility to asthma and respiratory infections.
K Bratke et al.
Clinical and experimental immunology, 177(1), 366-372 (2014-04-16)
Allergic asthma is a chronic disease of the airways associated with airway hyperresponsiveness, a variable degree of airflow obstruction, airway remodelling and a characteristic airway inflammation. Factors of the vitamin D axis, which include vitamin D metabolites and vitamin D

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico