F7129
5-Fluorocytosine
nucleoside analog
Sinónimos:
4-amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine
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About This Item
Fórmula empírica (notación de Hill):
C4H4FN3O
Número de CAS:
Peso molecular:
129.09
Beilstein/REAXYS Number:
127285
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.32
Productos recomendados
assay
≥99% (TLC)
mp
298-300 °C (dec.) (lit.)
antibiotic activity spectrum
fungi
mode of action
DNA synthesis | interferes
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
NC1=NC(=O)NC=C1F
InChI
1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
InChI key
XRECTZIEBJDKEO-UHFFFAOYSA-N
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General description
Chemical structure: nucleoside
Application
Used in studies on TMP biosynthesis.
Biochem/physiol Actions
Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
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