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E1752

Sigma-Aldrich

Estrone 3-(β-D-glucuronide) sodium salt

Sinónimos:

1,3,5(10)-Estratrien-17-one 3-glucuronide sodium salt

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About This Item

Fórmula empírica (notación de Hill):
C24H29NaO8
Número de CAS:
15087-01-1
Peso molecular:
468.47
Beilstein/REAXYS Number:
6043458
MDL number:
MFCD00271561
UNSPSC Code:
51111800
PubChem Substance ID:
24894430
NACRES:
NA.77

sterility

non-sterile

assay

≥99% (HPLC)

form

powder

technique(s)

ELISA: suitable

solubility

water: 20 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na+].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(O[C@@H]5O[C@@H]([C@@H](O)[C@H](O)[C@H]5O)C([O-])=O)ccc24

InChI

1S/C24H30O8.Na/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;/h3,5,10,14-16,18-21,23,26-28H,2,4,6-9H2,1H3,(H,29,30);/q;+1/p-1/t14-,15-,16+,18+,19+,20-,21+,23-,24+;/m1./s1

InChI key

PBULYLQKWDXDFZ-QHIGSJCSSA-M

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Application

Estrone 3-(β-D-glucuronide) sodium salt has been used as a standard:
  • to estimate estrone conjugate (E1Cs) from urine samples by enzyme immunoassays (EIAs)
  • to determine corticosterone metabolites from fecal and water samples by EIA
  • to estimate progesterone and estrogen levels in feces of Chinese goral by EIA

Biochem/physiol Actions

Estrone 3 glucuronide (E3G) is a urinary metabolite of estrogen. Higher levels of estrone 3 glucuronide are observed during the early onset of the fertile period of the menstrual cycle.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Rebecca C Miller et al.
Clinical chemistry, 50(5), 924-932 (2004-04-24)
Specific gravity (SG) may perform as well as creatinine (CR) correction for adjusting urinary hormone concentrations, as well as offer some advantages. We compared the two methods and applied them to US and Bangladeshi specimens to evaluate their use in
Kathleen A O'Connor et al.
American journal of physical anthropology, 145(4), 629-638 (2011-06-28)
Psychosocial stress is thought to negatively impact fecundity, but human studies are confounded by variation in nutrition and lifestyle. Baboons offer a useful model to test the effect of prolonged mild stress on reproductive indicators in a controlled setting. Following
Leonard F Blackwell et al.
Frontiers in public health, 6, 153-153 (2018-06-16)
The patterns of a woman's normal ovarian activity can take many forms from childhood to menopause. These patterns lie on a continuum ranging from no ovarian activity to a fully fertile ovulatory cycle, but among the other defined patterns are
Qinfang Shen et al.
Molecular and cellular biology, 29(14), 3881-3893 (2009-05-06)
In Caenorhabditis elegans, the central cell-killing process is essentially controlled by the interplay of four apoptotic factors: EGL-1/BH3-only protein, CED-9/Bcl2, CED-4/Apaf1, and CED-3/caspase. In cells destined to die, EGL-1 binds to CED-9 and results in the release of CED-4 from

Artículos

UHPLC Analysis of Conjugated Estrogens on Ascentis ® Express C18

Separation of Estriol 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) 17-sulfate dipotassium salt; Estriol 3-sulfate sodium salt; β-Estradiol 3,17-disulfate dipotassium salt, ≥95%; β-Estradiol 17-(β-D-glucuronide) sodium salt; β-Estradiol 3-(β-D-glucuronide) sodium salt; Estrone 3-(β-D-glucuronide) sodium salt; β-Estradiol 3-sulfate sodium salt, ≥93%; Estriol, ≥97%; Estrone 3-sulfate sodium salt, contains ~35% Tris as stabilizer; β-Estradiol, ≥98%; α-Estradiol, powder, ≥98% (TLC); Estrone, ≥99%

UHPLC Analysis of Conjugated Estrogens on Titan™ C18

The Titan C18 column provided efficient and rapid resolution of thirteen related estrogenic compounds. Ultra Ultra high purity solvents provided robust operation.

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