D9286

O,O-Diethyl O-(4-nitrophenyl) phosphate

≥90%, oil

• Sinónimos: O,O-Diethyl O-(4-nitrophenyl) phosphate, Diethyl p-nitrophenyl phosphate, Paraoxon, Paraoxon-ethyl
• Fórmula lineal: O₂NC₆H₄OP(O)(OC₂H₅)₂
• Número de CAS: 311-45-5
• Peso molecular: 275.20
• Beilstein/REAXYS Number: 1915526
• EC Number: 206-221-0
• MDL number: MFCD00007316
• UNSPSC Code: 12352202
• PubChem Substance ID: 24894279
• NACRES: NA.77

Propiedades

• assay: ≥90%
• form: oil
• color: yellow
• refractive index: n20/D 1.51 (lit.)
• density: 1.274 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
• InChI key: WYMSBXTXOHUIGT-UHFFFAOYSA-N
• Gene Information: human ... PON1(5444)

Descripción

Application

Paraoxon-ethyl has been used as a substrate in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein L3 (HDL3) to HDL2 in vivo.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Caution

air sensitive: handle under argon

Physical form

Oily liquid

Información de seguridad

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H300 + H310,H410
• pcodes: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter