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D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Sinónimos:

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Fórmula lineal:
C3H3O10P2Na5
Número de CAS:
102783-53-9
Peso molecular:
375.95
MDL number:
MFCD00070074
UNSPSC Code:
12352201
PubChem Substance ID:
24893967
NACRES:
NA.25

biological source

synthetic

Quality Level

200

form

powder

impurities

3-phosphoglyceric acid, essentially free

color

white to off-white

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 24.5-32.5% (anhydrous)

storage temp.

−20°C

SMILES string

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem/physiol Actions

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study
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The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation
Sitong Zhou et al.
Science advances, 5(5), eaaw4466-eaaw4466 (2019-06-01)
The tight coupling between cerebral blood flow and neural activity is a key feature of normal brain function and forms the basis of functional hyperemia. The mechanisms coupling neural activity to vascular responses, however, remain elusive despite decades of research.
Aabhas Mathur et al.
Transfusion, 56(12), 2941-2947 (2016-10-06)
Each unit of blood donated is processed and stored individually resulting in variability in the amount of red blood cells (RBCs) collected, RBC properties, and the 24-hour posttransfusion RBC survivability. As a result, each unit differs in its ability to
Vivek P Jani et al.
IEEE transactions on biomedical circuits and systems, 11(6), 1400-1405 (2017-10-06)
In 2013, nearly 15 million units of banked blood were transfused in the United States of America alone. Blood shortages are expected to increase globally. Donated blood is not equal due to differences in quality and deterioration rate. There are
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