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C5041

Sigma-Aldrich

6-Carboxyfluorescein diacetate

~95% purity (HPLC), powder

Sinónimos:

6-CFDA, 6-Carboxy-di-O-acetylfluorescein

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About This Item

Fórmula empírica (notación de Hill):
C25H16O9
Número de CAS:
3348-03-6
Peso molecular:
460.39
Beilstein/REAXYS Number:
67043
MDL number:
MFCD00036871
UNSPSC Code:
12171500
PubChem Substance ID:
24892748
NACRES:
NA.47

product name

6-Carboxyfluorescein diacetate, ≥95% (HPLC)

Quality Level

100
200

assay

≥95% (HPLC)

form

powder

color

white to yellow

solubility

chloroform/ethanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1

InChI

1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)

InChI key

QMOGCCYGOPYYNT-UHFFFAOYSA-N

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Application

6-Carboxyfluorescein diacetate has been used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin.
Fluorescent wavelengths λex 492nm; λemm 517nm in 0.1M Tris, pH 8.0.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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International journal of pharmaceutics, 530(1-2), 113-127 (2017-07-26)
The aim of the present research is to increase lipid solubility, metabolic stability and therapeutic efficacy of water soluble gemcitabine (GEM) via phospholipid complex (PC) formation. A novel phospholipid complex of GEM was successfully prepared and optimized. Physical interaction of
Douglas E Brenneman et al.
Journal of molecular neuroscience : MN, 47(2), 368-379 (2012-04-27)
Severe seizure activity is associated with recurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention to halt these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. In the
G Ricci et al.
Human reproduction (Oxford, England), 17(10), 2665-2672 (2002-09-28)
Apoptosis plays an important role in regulating spermatogenesis. However, the biological significance of apoptosis in ejaculated sperm is not yet clear. This study set out to investigate how apoptosis correlates with semen quality and the presence of seminal leukocytes. Fifty-seven
Evaluation of sperm quality snakes Erythrolamprus poecilogyrus sublineatus (Cope, 1860) (Serpentes, Dipsadidae).
Silva AC, et al.
Brazilian journal of biology = Revista brasleira de biologia, doi: 10-doi: 10 (2017)
Garry R Smith et al.
Journal of molecular neuroscience : MN, 52(3), 446-458 (2013-11-28)
Severe seizure activity is associated with reoccurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention with these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. We have optimized
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