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A5626

Sigma-Aldrich

Acetylthiocholine chloride

≥99% (TLC), powder

Sinónimos:

(2-Mercaptoethyl)trimethylammonium chloride acetate

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About This Item

Fórmula lineal:
CH3COSCH2CH2N(CH3)3Cl
Número de CAS:
6050-81-3
Peso molecular:
197.73
EC Number:
227-953-7
MDL number:
MFCD00038727
UNSPSC Code:
12352204
PubChem Substance ID:
24278219
NACRES:
NA.83

assay

≥99% (TLC)

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

SMILES string

[Cl-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

GZYVLKKMMDFCKR-UHFFFAOYSA-M

Gene Information

human ... ACHE(43)

Application

Acetylthiocholine chloride has been used to determine the acetylcholine esterase activity of semen exosomes (SE). It has also been used as a substrate for acetylcholine esterase in microcalorimetric study of its kinetic parameters.

Biochem/physiol Actions

Acetylcholinesterase (AChE) enzyme plays an important physiological role in the neurotransmission process.
Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Tanja Botić et al.
European journal of medicinal chemistry, 136, 294-304 (2017-05-16)
The brominated pyrroloiminoquinone alkaloids discorhabdins B, L and G and 3-dihydro-7,8- dehydrodiscorhabdin C, isolated from methanol extracts of two specimens of Latrunculia sp. sponges collected near the Antarctic Peninsula, are here demonstrated for the first time to be reversible competitive
Alexandra Raileanu et al.
Journal of nanoscience and nanotechnology, 18(10), 6905-6912 (2018-06-30)
Here we report on the fabrication and characterization of cluster-assembled nanostructured zirconia electrodes for the electrochemical detection of enzymatically produced thiocholine. Zirconia nanostructures are produced by Supersonic Cluster Beam Deposition on thin gold films. This technique enables nanoscale control of
Roberto M Maciel et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 559-568 (2016-10-04)
The present study investigated the protective effect of quercetin (Querc) on memory, anxiety-like behavior and impairment of ectonucleotidases and acetylcholinesterase (AChE) activities in brain of streptozotocin-induced diabetic rats (STZ-diabetes). The type 1 diabetes mellitus was induced by an intraperitoneal injection
Lindon W K Moodie et al.
Organic & biomolecular chemistry, 14(47), 11220-11229 (2016-11-15)
The marine secondary metabolite stryphnusin (1) was isolated from the boreal sponge Stryphnus fortis, collected off the Norwegian coast. Given its resemblance to other natural acetylcholinesterase antagonists, it was evaluated against electric eel acetylcholinesterase and displayed inhibitory activity. A library
Nadin Aftim et al.
Talanta, 174, 414-419 (2017-07-26)
Molecularly imprinted polymers (MIPs) for phosmet insecticide were synthesized by batch polymerization. The affinity of functional monomers to phosmet was tested using an original method involving an electrochemical biosensor based on acetylcholinesterase inhibition. It was demonstrated that association of phosmet
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