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A3253

Sigma-Aldrich

Ala-Pro hydrate

≥98% (TLC), suitable for ligand binding assays

Sinónimos:

L-Alanyl-L-proline hydrate

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About This Item

Fórmula empírica (notación de Hill):
C8H14N2O3 · xH2O
Número de CAS:
13485-59-1
Peso molecular:
186.21 (anhydrous basis)
Beilstein/REAXYS Number:
3546017
EC Number:
236-795-8
MDL number:
MFCD00150505
UNSPSC Code:
12352202
PubChem Substance ID:
24890751
NACRES:
NA.26

product name

Ala-Pro hydrate,

assay

≥98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

O.C[C@H](N)C(=O)N1CCC[C@H]1C(O)=O

InChI

1S/C8H14N2O3.H2O/c1-5(9)7(11)10-4-2-3-6(10)8(12)13;/h5-6H,2-4,9H2,1H3,(H,12,13);1H2/t5-,6-;/m0./s1

InChI key

SSUWZOPYGFOQJA-GEMLJDPKSA-N

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Biochem/physiol Actions

Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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H Ke et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(8), 3324-3328 (1993-04-15)
Cyclophilin is a binding protein for the immunosuppressive drug cyclosporin A and is also an enzyme with peptidyl-prolyl cis-trans isomerase activity. The crystal structure of cyclophilin A complexed with the substrate Ala-Pro has been determined and refined to an R
R Hanai et al.
Journal of chromatography, 394(2), 273-278 (1987-05-22)
The "elution-band relaxation method" has been applied to the analysis of the cis-trans kinetics isomerization of the proline of L-Ala-L-Pro using reversed-phase liquid chromatography. A procedure suitable for cases where neither isomer can be injected separately is described.
Yan Chen et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 22(1), 9-14 (2006-01-25)
A micro-reactor system with continual spectrophotometric detection has been operated in Sequential Injection lab-on-valve (SI-LOV) mode and applied to enzyme kinetics and inhibition studies, using acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE) as model systems. With the advantages of automation, real-time
Byung Jin Byun et al.
The journal of physical chemistry. B, 114(44), 14077-14086 (2010-10-19)
Conformational preferences and prolyl cis-trans isomerizations of the X-Pro motifs (Ac-X-Pro-NHMe, X = Ala and Aib) are explored using the meta-hybrid functional M06-2X and the double-hybrid functional B2PLYP-D with empirical dispersion corrections in the gas phase and in water, where
Young-Ok Kim et al.
The Journal of general and applied microbiology, 55(5), 345-350 (2009-11-27)
Citrobacter braakii produced an intracellular acid glucose phosphatase (AgpC) which was purified 986 fold to homogeneity with the specific activity of 286 units/mg. AgpC hydrolyzed a wide variety of phosphorylated compounds with high activity for glucose-1-phosphate and glucose-6-phosphate. The optimum
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