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Key Documents

68841

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

Mr ~20,000

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About This Item

Número de CAS:
9011-18-1
MDL number:
MFCD00081551
UNSPSC Code:
12352201
NACRES:
NA.25

form

powder

mol wt

Mr ~20,000

composition

Sulfur Content, 16.0-20.0%

loss

≤10% loss on drying

solubility

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

storage temp.

room temp

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General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Dextran sulfate can interact and bind to lipids making it useful in protein isolation techniques to remove contaminating lipid molecules.

Preparation Note

Sigma dextrans are derived from Leuconostoc mesenteroides.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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In avian species, blood IgY is selectively incorporated into the yolks of maturing oocytes, although the precise mechanism is poorly understood. Our previous study showed that 22% of i.v.-injected heterologous chicken IgY (cIgY) was incorporated into egg yolks of Japanese
Aaron H Rose et al.
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An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and

Artículos

FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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