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Key Documents

333M-1

Sigma-Aldrich

Spectrin (RBC2/3D5) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

RBC2/3D5, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (333M-14)
vial of 0.5 mL concentrate (333M-15)
bottle of 1.0 mL predilute (333M-17)
vial of 1.0 mL concentrate (333M-16)
bottle of 7.0 mL predilute (333M-18)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:100

isotype

IgG1κ

control

bone marrow

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... SPTA1(6708)

General description

Spectrin is a cytoskeletal protein which is found in muscles, red blood cells and red cell precursors. Anti-Spectrin antibody is useful in the diagnosis of erythroid leukemias.

Quality


IVD

IVD

IVD

RUO

Linkage

Spectrin Positive Control Slides, Product No. 333S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Y Sadahira et al.
Journal of clinical pathology, 52(12), 919-921 (2000-03-11)
To investigate whether spectrin can be used as an immunohistochemical marker for erythroid precursors in routinely processed paraffin embedded bone marrow sections. Bone marrow biopsies and clot sections were stained with rabbit antihuman erythrocyte spectrin antibodies, specific for erythroid cells
N Terada et al.
Journal of anatomy, 190 ( Pt 3), 397-404 (1997-04-01)
A quick-freezing and deep-etching method in combination with erythrocyte splitting was used to examine the cytoplasmic aspect of whole-mount human erythrocyte membranes. Various external forces induced alterations in membrane skeletal organisation during the splitting procedure. The initial change was elongation
V Nehls et al.
The American journal of pathology, 142(5), 1565-1573 (1993-05-01)
Expression of the erythrocyte anion exchanger band 3, and ankyrin and spectrin, two cytoskeletal proteins of the red blood cell membrane, was studied by immunofluorescence using: 1) smears of human bone marrow from healthy donors and from a patient with
M Müller et al.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 48(1), 51-57 (2001-08-23)
In an immunohistological/cytological study of canine bone marrow, the aim was to demonstrate canine erythroid cells with the help of various commercially available antibodies against human antigens (monoclonal antibody against glycophorin A, polyclonal antibodies against haemoglobin and spectrin). In order

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