25810

Chloroperoxidase from Caldariomyces fumago

aqueous suspension, brown, >10,000 U/mL

• Sinónimos: Chloride Peroxidase, Chloride:hydrogen-peroxide oxidoreductase
• Número de CAS: 9055-20-3
• Comisión internacional de enzimas: 1.11.1.10 (BRENDA, IUBMB)
• MDL number: MFCD00130774
• UNSPSC Code: 12352204
• NACRES: NA.54

Propiedades

• biological source: fungus (Caldariomyces fumago)
• form: aqueous suspension
• concentration: >10,000 U/mL
• color: brown
• storage temp.: 2-8°C

Descripción

General description

Chloroperoxidase (CPO) is a major heme-containing, synthetic and versatile enzyme, obtained from Caldariomyces fumago.

Application

A useful alternative to lactoperoxidase for ¹³¹I ion labeling studies, for bromination of proteins, and for ³⁶Cl labeling of macromolecules in long-term isolation procedures.

Biochem/physiol Actions

Chloroperoxidase (CPO) helps in the catalysis of oxidation reactions with the help of hydrogen peroxide. It displays peroxidase, catalase and cytochrome P450-like functions. CPO also plays a role in catalyzing halogenation reactions.

Unit Definition

1 U corresponds to the amount of enzyme which converts 1 μmol of monochlorodimedone to dichlorodimedone per minute at pH 2.75 and 25 °C in the presence of KCl and H₂O₂.

Physical form

enthält 0.1 M Natriumphosphat pH 4.0

Other Notes

Oxidation of aminopyrine; Chloroperoxidase, a peroxidase with potential; Chloroperoxidase-catalyzed asymmetric transformations.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves