16842

Sodium (S)-β-hydroxyisobutyrate

≥96.0%

• Sinónimos: (S)-β-Hydroxy-isobutyric acid sodium salt, (S)-3-Hydroxy-2-methylpropionic acid sodium salt, S-HIBA, R-β-HIBA-Na, Sodium (S)-3-hydroxy-2-methylpropionate
• Fórmula empírica (notación de Hill): C₄H₇NaO₃
• Número de CAS: 1893416-17-5
• Peso molecular: 126.09
• MDL number: MFCD17215930
• UNSPSC Code: 12352106
• PubChem Substance ID: 329751395
• NACRES: NA.25

Propiedades

• assay: ≥96.0% (GC); ≥96.0%
• optical purity: enantiomeric excess: ≥98.0%
• composition: sodium, 17.5-19.0%
• storage temp.: 2-8°C
• SMILES string: [Na+].C[C@@H](CO)C([O-])=O
• InChI: 1S/C4H8O3.Na/c1-3(2-5)4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1/t3-;/m0./s1
• InChI key: RBJZIQZDAZLXEK-DFWYDOINSA-M

Descripción

Application

3-Hydroxyisobutyrate (HIBA) may be used to study the distribution, characterization and kinetics of enzymes involved in branched chain amino acid metabolism such as 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). (S)-β-hydroxyisobutyrate may be used in stereospecific studies.

Biochem/physiol Actions

Metabolite in valine, leucine and isoleucine degradation, a reactant of enzymes 3-hydroxyisobutyrate dehydrogenase (EC: 1.1.1.31), 3-hydroxyacyl-CoA dehydrogenase (EC: 1.1.1.35) and 3-hydroxyisobutyryl-CoA hydrolase (EC: 3.1.2.4). Enantiomeric ratio can be used in diagnosis of metabolic diseases, e.g. 3-hydroxyisobutyric aciduria.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable