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04668

Sigma-Aldrich

O-Phospho-L-homoserine lithium salt

≥95% (TLC)

Sinónimos:

O-Phosphono-L-homoserine lithium salt, L-2-Amino-4-hydroxybutyric acid 4-phosphate lithium salt, L-Homoserine O-phosphate lithium salt, H-Hse(PO3H2)-OH

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About This Item

Fórmula empírica (notación de Hill):
C4H10NO6P · xLi+
Número de CAS:
4210-66-6
Peso molecular:
199.10 (free acid basis)
UNSPSC Code:
12352209
NACRES:
NA.26

Quality Level

100

assay

≥95% (TLC)

form

powder

optical activity

[α]/D -18.0±2.0°, c = 1 in H2O

color

white to off-white

storage temp.

−20°C

InChI

1S/C4H10NO6P/c5-3(4(6)7)1-2-11-12(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1

InChI key

FXDNYOANAXWZHG-VKHMYHEASA-N

Biochem/physiol Actions

Metabolite in glycine, serine and threonine metabolism. In higher plants, O-phosphohomoserine represents a branch point between the methionine and threonine biosynthetic pathways.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCBK8277
BCBK8277V

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Hongtao Li et al.
Science (New York, N.Y.), 315(5814), 1000-1003 (2007-02-17)
Pathogenic bacteria use the type III secretion system to deliver effector proteins into host cells to modulate the host signaling pathways. In this study, the Shigella type III effector OspF was shown to inactivate mitogen-activated protein kinases (MAPKs) [extracellular signal-regulated
T Zhou et al.
Structure (London, England : 1993), 8(12), 1247-1257 (2001-02-24)
Homoserine kinase (HSK) catalyzes an important step in the threonine biosynthesis pathway. It belongs to a large yet unique class of small metabolite kinases, the GHMP kinase superfamily. Members in the GHMP superfamily participate in several essential metabolic pathways, such
Oliver Kreft et al.
Plant physiology, 131(4), 1843-1854 (2003-04-15)
In plants, metabolic pathways leading to methionine (Met) and threonine diverge at the level of their common substrate, O-phosphohomoserine (OPHS). To investigate the regulation of this branch point, we engineered transgenic potato (Solanum tuberosum) plants affected in cystathionine gamma-synthase (CgS)
D Bartlem et al.
Plant physiology, 123(1), 101-110 (2000-05-12)
In higher plants, O-phosphohomoserine (OPH) represents a branch point between the methionine (Met) and threonine (Thr) biosynthetic pathways. It is believed that the enzymes Thr synthase (TS) and cystathionine gamma-synthase (CGS) actively compete for the OPH substrate for Thr and
G E Gilbert et al.
Biochemistry, 32(37), 9577-9585 (1993-09-21)
Phosphatidylserine, a negatively charged lipid, is exposed on the platelet membrane following cell stimulation, correlating with the expression of factor VIII receptors. We have explored the importance of the negative electrostatic potential of phosphatidylserine vs chemical moieties of phosphatidylserine for
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